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KMID : 0869020150180010009
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Journal of Korean Orthopaedic Research Society
2015 Volume.18 No. 1 p.9 ~ p.17
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Surface Characteristics and Biocompatibility of Micro Arc Oxidized Titanium Alloy
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Lim Young-Wook
Lee Eun-Sang
Kim Yong-Sik
Song Kwang-Yun
Kwon Soon Yong
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Abstract
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Purpose: The aim of this research was to characterize micro arc oxidized titanium (MAO-Ti), accompanied by biocompatibility test in vivo as well as in vitro in comparison to the different types of surface modification; machined, blasted and plasma spray.
Materials and Methods: XRD and SEM investigations were performed in order to assess the structure and morphology. Biologic and morphologic responses to the osteoblast cell lines (Saos-2) were then examined, using Promega?? proliferation assay, alkalinephosphatase activity, αv??3 integrin expression and cytoskeleton staining (Rhodamine-Phallodine). The analysis of gene expression for osteocalcin and collagen I was done through RT-PCR.
Results: MAO-Ti showed more activity on osteointegration and cell differentiation compared to other types of surface modification.
Conclusion: In summary, MAO-Ti appears to exhibit more favorable biocompatibility than the compared groups in vitro and in vivo as well.
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KEYWORD
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Micro Arc Oxidized (MAO), Biocompatibility, Titanium Alloy
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